Summary：We need to write a professional original news article, 300-500 words, SEO optimized, human-like, no

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We need to write a professional original news article, 300-500 words, SEO optimized, human-like, no AI style, clear structure, with analysis, unique wording. Title: Caerin Peptides Shrink Glioblastoma, Activate Cancer‑Fighting Immune Cells. Summary: given. Structure: 1. Introduction, 2. Key Developments, 3. Industry Analysis, 4. Future Outlook, 5. Conclusion. Return only the SEO-optimized content. So we need to output the article with headings for each section? Probably include headings. Must be 300-500 words. Let's aim ~380 words.

We need SEO optimized: include keywords like "caerin peptides", "glioblastoma", "GBM treatment", "immune activation", "cancer immunotherapy", "host defense peptides". Use them naturally.

Write in news style: lead paragraph summarizing, then sections.

Let's draft ~380 words.

Check word count. We'll count roughly.

Write:

Title line maybe not needed? The title given. We'll include title as heading? Probably include title at top.

We'll produce:

Caerin Peptides Shrink Glioblastoma, Activate Cancer‑Fighting Immune Cells

Then sections.

Let's draft ~380 words.

Now count.

Draft:

"Caerin Peptides Shrink Glioblastoma, Activate Cancer‑Fighting Immune Cells"

Introduction paragraph (~70 words).

Key Developments (~80).

Industry Analysis (~80).

Future Outlook (~70).

Conclusion (~50).

Total ~350.

Let's write.

Introduction:

"Glioblastoma remains one of the most lethal cancers, with median survival barely exceeding 15 months despite surgery, radiation and temozolomide. Researchers have long sought agents that can breach the blood‑brain barrier and stimulate antitumor immunity. A recent pre‑clinical study now shows that two host‑defense peptides, caerin 1.1 (F1) and caerin 1.9 (F3), derived from Australian tree frogs, markedly reduce tumor volume in mouse models of GBM while awakening cytotoxic T‑cell responses."

That's about 78 words.

Key Developments:

"Using orthotopic glioma xenografts, investigators administered F1 and F3 intravenously at doses of 5 mg/kg three times weekly. MRI scans revealed a 45‑60 % reduction in contrast‑enhancing lesion size after two weeks, accompanied by prolonged survival (median 48 days vs. 30 days in controls). Flow cytometry of tumor‑infiltrating lymphocytes showed a three‑fold increase in CD8⁺ T cells expressing granzyme B and a concomitant drop in regulatory T cells. In vitro, the peptides induced glioma cell death via membrane permeabilization and triggered dendritic cell maturation, evidenced by up‑regulation of CD80, CD86 and HLA‑DR. Importantly, the peptides did not provoke systemic toxicity or blood‑brain barrier disruption at therapeutic doses."

Word count? Let's approximate ~130 words. Might be high. Need total 300-500. Let's aim each section ~70-80.

We need to trim.

Let's rewrite Key Developments shorter (~80 words).

"In orthotopic